Globally, 60–90% of adults carry HSV-1, making it among the most common viral infections. The challenge lies in its frequent recurrences, which can significantly impact quality of life. While a complete cure remains elusive, proactive lifestyle and dietary habits can substantially reduce the frequency of outbreaks.
The Role of Immunity and Nutrition in Prevention
Cold sores are closely tied to immune function and nutritional status. Poor lifestyle habits—such as irregular sleep, chronic stress, overwork, or poor diet—can weaken immunity and trigger HSV-1 reactivation. Hormonal fluctuations also play a role in triggering outbreaks.
Lysine: A Key Nutrient in Controlling Outbreaks
Among the dietary strategies for managing cold sores, lysine, an essential amino acid, stands out. Lysine inhibits the activity of arginine, another amino acid that promotes HSV-1 replication. Studies suggest that daily intake of 900–1,000 mg of lysine may reduce recurrence rates in more than 80% of patients. During outbreaks, higher doses of 2,000–3,000 mg daily may help shorten healing time, but should be taken under medical guidance.
Lysine is abundant in animal-based proteins. Poultry like chicken breast, beef, pork, and fish such as salmon, mackerel, and cod are excellent sources. Dairy products, including cheese, milk, yogurt, and eggs, also provide significant amounts of lysine.

Boosting Immunity with Vitamins and Minerals
In addition to lysine, other nutrients play a vital role in supporting immune health. Vitamin C, found in citrus fruits like oranges, kiwi, strawberries, and vegetables like broccoli, strengthens the body’s defenses against infections. Zinc, which activates immune cells and curbs viral replication, is readily available in oysters, beef, and legumes.
Omega-3 fatty acids and antioxidants further enhance immune resilience. Foods rich in omega-3s, such as salmon, mackerel, flaxseeds, and chia seeds, help reduce inflammation and aid recovery. Antioxidant-rich foods like berries, green tea, spinach, and carrots protect cells from damage and bolster immune function.
Practical Steps for Prevention
While HSV-1 cannot be eradicated, its impact can be minimized through consistent care. A balanced diet, regular sleep, stress management, and avoiding known triggers like excessive sun exposure are essential. Prioritizing nutrient-rich foods and healthy habits can reduce both the frequency and severity of cold sore outbreaks, improving overall well-being.
Haeun Oh, HEALTH IN NEWS TEAM
press@hinews.co.kr